Resource Type

Journal Article 399

Year

2023 26

2022 30

2021 29

2020 20

2019 27

2018 20

2017 27

2016 16

2015 19

2014 23

2013 13

2012 13

2011 5

2010 9

2009 13

2008 20

2007 21

2006 21

2005 9

2004 7

open ︾

Keywords

genetic algorithm 33

algorithm 14

optimization 14

immunotherapy 7

artificial neural network 5

Genetic algorithm 4

immune checkpoint inhibitor 4

neural network 4

COVID-19 3

different 3

meta-heuristic algorithm 3

3D printing 2

Algorithm 2

BP algorithm 2

BP neural network 2

FEM 2

HY-2 2

PD-L1 2

Support vector machine (SVM) 2

open ︾

Search scope:

排序: Display mode:

Application of a Novel Fuzzy Clustering Method Based on Chaos Immune Evolutionary Algorithm for Edge

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 1,   Pages 85-89 doi: 10.1007/s11465-005-0023-6

Abstract:

A novel fuzzy clustering method based on chaos immune evolutionary algorithm (CIEFCM) is presenteddisturbance amplitude is adjusted step by step, which greatly improves the colony diversity of the immuneevolution algorithm (IEA).fuzzy edge and exiguous edge but can evidently improve the searching efficiency of fuzzy clustering algorithm

Keywords: disturbance amplitude     disturbance     diversity     generation     processing    

Optimization of thread partitioning parameters in speculative multithreading based on artificial immunealgorithm

Yu-xiang LI,Yin-liang ZHAO,Bin LIU,Shuo JI

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 3,   Pages 205-216 doi: 10.1631/FITEE.1400172

Abstract: We use the artificial immune algorithm (AIA) to search for the optimal solution.

Keywords: Speculative multithreading     Thread partitioning     Artificial immune algorithm    

Evolutionary Immune Mechanism and Its Application on Temporal Sequential Pattern Mining

Yang Bingru,Qin Yiqing,Song Zefeng

Strategic Study of CAE 2008, Volume 10, Issue 4,   Pages 84-89

Abstract: Next the evolutionary immune mechanism in KDD is illustrated, based on a comparison between the dynamicmining process and biological immune process.Additionally how to apply the approach to temporal sequential

Keywords: dynamic data mining     immune algorithm     dynamic mining process     evolutionary immune mechanism     temporal    

Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 33-42 doi: 10.1007/s11684-019-0735-3

Abstract: Immunotherapy has recently led to a paradigm shift in cancer therapy, in which immune checkpoint inhibitorsnon-specific activation of effector T cells, ICIs are remarkably associated with a substantial risk of immune-related

Keywords: cancer     immunotherapy     immune checkpoint inhibitors     immune-related adverse events     review    

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 269-279 doi: 10.1007/s11684-018-0621-4

Abstract: NK cell activation, well known for its role in the immune surveillance against tumor and pathogen-infectedUnder the setting of liver diseases, NK cells are of great importance for stimulating or inhibiting immuneresponses, leading to either immune activation or immune tolerance.

Keywords: natural killer cell     phenotype     immune activation     immune tolerance     liver diseases    

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 816-819 doi: 10.1007/s11684-020-0823-4

Heterogeneity of the tumor immune microenvironment and clinical interventions

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 617-648 doi: 10.1007/s11684-023-1015-9

Abstract: Heterogeneity of the tumor immune microenvironment and clinical interventions

Keywords: Heterogeneity tumor immune    

Molecular classification and precision therapy of cancer: immune checkpoint inhibitors

Yingyan Yu

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 229-235 doi: 10.1007/s11684-017-0581-0

Abstract: MSI-H status due to dMMR and characterized by increased neoantigen load, which elicits intense host immune

Keywords: molecular classification     precision medicine     pembrolizumab     PD-1/PD-L1     MSI-H    

Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infected

Xinghua Gao, Hongduo Chen

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 1-5 doi: 10.1007/s11684-014-0309-3

Abstract: instance, fever-range temperature (39β°C to 40β°C) can modulate the activities of immuneCytotoxic temperature (>43β°C) can create an antigen source to induce an anti-tumor immune

Keywords: hyperthermia     HPV     immune response     virus     tumor    

SARS-CoV-2 variants, immune escape, and countermeasures

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 196-207 doi: 10.1007/s11684-021-0906-x

Abstract: Although many countries have promoted roll-out vaccination, the immune barrier has not yet been fully

Keywords: SARS-CoV-2     COVID-19     vaccine     immune escape     breakthrough     prevention    

Multi-target combinatory strategy to overcome tumor immune escape

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 208-215 doi: 10.1007/s11684-022-0922-5

Abstract: Immune therapy has become the fourth approach after surgery, chemotherapy, and radiotherapy in cancerMany immune checkpoints were identified in the last decade since ipilimumab, which is the first immuneHowever, fewer people are benefitting from immune checkpoint inhibitor treatment in solid cancers.Along with the characterization of more immune checkpoints, the combinatory treatment of multi-immuneIn this work, the author focuses on the combination therapy of multiple immune checkpoints (does not

Keywords: immune checkpoints     multi-target     immune escape     immune-related adverse events     combination therapy    

Estimating the number of Chinese cancer patients eligible for and benefit from immune checkpoint inhibitors

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 773-783 doi: 10.1007/s11684-021-0902-1

Abstract: The total number of cancer patients who are eligible for and will benefit from immune checkpoint inhibitorspatients with eligibility and response to ICIs based on the 2015 Chinese cancer statistics and the immune

Keywords: benefit     China     eligibility     immune checkpoint inhibitor     public health    

Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 333-346 doi: 10.1007/s11684-020-0776-7

Abstract: Upon viral invasion, the innate immune system responds rapidly and plays a key role in activating theadaptive immune system.In the innate immune system, the interactions between pathogen-associated molecular patterns and hostMacrophages, dendritic cells, and natural killer cells are the principal innate immune components thatThis knowledge provides an enhanced understanding of the innate immune response to RNA viral infections

Keywords: innate immune     viral infection     intercellular signaling     metabolic changes     epigenetic changes    

Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases

Zhen Xiang, Yingyan Yu

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 24-31 doi: 10.1007/s11684-019-0679-7

Abstract: Immune checkpoint inhibitors are a promising strategy in the treatment of cancer, especially advancedHowever, not all patients are responsive to immune checkpoint inhibitors.The response rate depends on the immune microenvironment, tumor mutational burden (TMB), expression levelof immune checkpoint proteins, and molecular subtypes of cancers.provide large volumes of data, which allow researchers to explore responsive or resistant biomarkers of immune

Keywords: immune checkpoint blockade     sensitivity     resistance     data mining    

Research on economic operation of microgrid with high temperature energy storage system

Luo Yi and Zhang Lijuan

Strategic Study of CAE 2015, Volume 17, Issue 1,   Pages 74-80

Abstract: The improved immune particle swarm algorithm is used to solve the proposed model, and then field application

Keywords: high temperature energy storage system; microgrid; economic operation; optimized dispatching; improved immuneparticle swarm algorithm    

Title Author Date Type Operation

Application of a Novel Fuzzy Clustering Method Based on Chaos Immune Evolutionary Algorithm for Edge

Journal Article

Optimization of thread partitioning parameters in speculative multithreading based on artificial immunealgorithm

Yu-xiang LI,Yin-liang ZHAO,Bin LIU,Shuo JI

Journal Article

Evolutionary Immune Mechanism and Its Application on Temporal Sequential Pattern Mining

Yang Bingru,Qin Yiqing,Song Zefeng

Journal Article

Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Journal Article

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Journal Article

Persistence of humoral and cellular immune response after SARS-CoV-2 infection: opportunities and challenges

Tangchun Wu

Journal Article

Heterogeneity of the tumor immune microenvironment and clinical interventions

Journal Article

Molecular classification and precision therapy of cancer: immune checkpoint inhibitors

Yingyan Yu

Journal Article

Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infected

Xinghua Gao, Hongduo Chen

Journal Article

SARS-CoV-2 variants, immune escape, and countermeasures

Journal Article

Multi-target combinatory strategy to overcome tumor immune escape

Journal Article

Estimating the number of Chinese cancer patients eligible for and benefit from immune checkpoint inhibitors

Journal Article

Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Journal Article

Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases

Zhen Xiang, Yingyan Yu

Journal Article

Research on economic operation of microgrid with high temperature energy storage system

Luo Yi and Zhang Lijuan

Journal Article